Piezo1 ion channels mediate the conversion of mechanical forces into electrical signals and are critical for responsiveness to touch in metazoans.The apparent mechanical sensitivity of Piezo1 varies substantially across cellular environments, stimulating methods and protocols, raising the fundamental questions of what precise physical stimulus acti

Biomolecular condensates are formed by liquid-liquid phase separation (LLPS) of multivalent molecules.LLPS from a single ("homotypic") constituent is governed by buffering: above a threshold, free monomer concentration is clamped, with all added molecules entering the condensed phase.However, both experiment and theory demonstrate that buffering fa

Traffic sign detection plays a pivotal role in autonomous driving systems.The intricacy of the detection model necessitates high-performance hardware.Real-world traffic environments exhibit considerable variability and diversity, posing challenges for effective feature extraction by the model.Therefore, it is imperative to develop a detection model

Prolonging working lives, in the context of an ageing population, has been seen as a good way to improve, on the one hand, the financial sustainability of the public pension system and, on the other hand, the Light Plugs adequacy of the pension benefit.As the literature has shown, even when measures for extending working lives have been taken, the